Acelagen Inc.
(January 2002)
1601 Nicholasville Road, Lexington, KY 40503-1470
859/278-3226
Develops technology for high-throughput production of a range of DNA products for the biomedical research industry and provides molecular biology support for academic and commercial biomedical research laboratories. Based on the research of Colin Wilson, pharmacy.
Affinity Labeling Technologies Inc.
(January 2000)
235 Bolivar Street, Lexington, KY 40508-2931
859/388-9445
www.altcorp.com
Develops nucleotide photoaffinity probes—radioactive compounds used in research and diagnosis of periodontal disease. When exposed to ultraviolet light, these photoprobes bind to the protein, allowing it to be tagged for identification. Founded in 1998 and based on the research of Boyd Haley, chemistry.
Affitech Laboratories Inc.
(January 2002)
3332 Pastern Court, Lexington, KY 40513-1004
www.affitech.com
Focuses on isolation of biologically active peptides, hormones and enzymes from E. coli and other microorganisms, and development of enzyme immunoassays for these substances. Provides technology to other pharmaceutical companies for in-house use or for further commercialization. Based on the research of Hsin-Hsiung Tai, pharmacy.
Allylix Inc.
(June 2007)
1500 Bull Lea Road, Lab 7, Lexington, KY 40511
859.243.5777 (lab), 859.510.332.9142 (cell)
Carolyn Fritz, cfritz@allylix.com
www.allylix.com
Allylix is combining leading edge research in molecular genetics, biochemistry and structural biology from the University of Kentucky and The Salk Institute for Biological Studies to produce natural products called terpenes for the flavor & fragrance and insect repellent markets. Using its extensive intellectual property, Allylix can create diverse collections of fine chemicals, especially chiral chemicals, rapidly generating molecules that possess the properties of natural products, as well as scale up production of high-value single entity compounds.
Bio-Products International Corporation
(April 1998)
235 Bolivar Street, Lexington, KY 40508-2931
859/388-9445
Develops nucleotide photoaffinity analogs for use as research tools for identifying proteins and in studying DNA/RNA binding proteins at the molecular level. Merged into Affinity Labeling Technologies Inc. Founded in 1994 and based on the research of Boyd Haley, pharmacy.
CarboLex Inc.
(July 2002)
Carbon Solutions Inc.
(December 2000)
5094 Victoria Hill Drive, Riverside, CA 92506-1450
909/787-2044
www.carbonsolution.com
Produces chemically modified materials based on carbon nanotube technology, including chemically modified single-wall nanotubes that are soluble in organic solvents. Based on the research of Robert Haddon, formerly in chemistry.
Cardiojustable L.L.C.
(August 2004)
2260 Carolina Lane, Lexington, KY 40513-1827
859/323-6494
Cardiojustable develops specialized cardiovascular devices for pediatric cardiac surgery. Cardiojustable is currently developing the first-ever adjustable vascular graft for control of pulmonary blood flow for infants with single ventricle physiology. Based on the research of William Douglas, Surgery.
CellSignals Inc.
(June 2002)
1275 Kinnear Road, Columbus, OH 43212-1155
614/340-1845
Develops pharmaceuticals by investigating biochemical agents that have the potential to promote hemostasis and stop bleeding in trauma victims. Based on the research of Melissa Shieh.
customKYnetics Inc.
(February 2003)
DeNovo Inc.
(December 1998)
3233 Raven Circle, Lexington, KY 40502-3305
859/257-1718
Develops promising therapeutic agents and brings them to a stage where their safety and efficacy can be assessed. Founded in 1997 and based on the research of Peter Crooks, pharmacy.
DSP Techniques Inc.
(January 2003)
3121 Althorp Way, Lexington, KY 40509-2423
Commercializes digital signal processing (DSP) technologies, including re-configurable DSP architectures and nonlinear signal modeling and fingerprinting. Based upon the research conducted by Bruce Walcott and Ernest Seagraves, engineering.
Enzymax L.L.C.
(September 2006)
GenApps Inc.
(October 1999)
IDEXX Veterinary Services Inc., d.b.a. Equine Biodiagnostics
(October 1999)
Intranasal Technology Inc.
(January 2002)
K&K Biosciences Inc.
(March 1998)
2504 Century Lane, Chadds Ford, PA 19317-8960
610/399-8625
Develops drugs for various neurological or brain disorders such as epilepsy and Parkinson's disease. Founded in 1996 and based on the work of P.K. Kadaba, formerly in pharmacy.
LevTech Inc.
(October 2004)
The Lexington Carbon Company LLC
(October 1999)
11302 Strang Line Rd., Lenexa, KS, 66215-4041
913/317-4100
Develops specialty carbon materials for gas and liquid separation, energy conversion systems, environmental processing of gas and liquid streams, military and industrial protective filters, and medicine, food and beverage processing. The predecessor-in-interest company was founded in 1994 by the late Frank Derbyshire and Don Challman, and the company's products are based on the research of Derbyshire, Marit Jagtoyen and Geoff Kimber, formerly of the Center for Applied Energy Research.
Lumenware L.L.C.
(February 2007)
M2 Technologies Inc.
(January 2007)
NanoMed Pharmaceuticals®
(October 2007)
7107 Elm Valley Drive, Room B1210, Kalamazoo, Michigan 49009
269/488-8525
www.nanomedpharm.com
NanoMed Pharmaceuticals® is an early-stage specialty pharmaceutical company dedicated to developing improved therapeutic and diagnostic products to treat or detect cancer and other serious diseases. The company’s core technology, Nanotemplate Engineering, is a nanoparticle manufacturing technology used to formulate small molecules, peptides, proteins, plasmid DNA, and diagnostic agents. NanoMed was founded in 2000 by UK researchers Russell J. Mumper and Michael Jay.
New Ace Research Company Inc.
(November 2001)
P.O. Box 273, Versailles, KY, 40383-0273
859/873-4739
Develops new technologies and treatments for use in various human and animal diseases. Based on the research of David Granstrom and Tom Tobin, Maxwell H. Gluck Equine Research Center.
New Millennium Pharmaceutical Research Inc.
(June 2000)
4999 Hartland Parkway, Lexington, KY 40515-1121
859/272-8684
Develops nasal-delivery systems for selected medication, including an innovative drug to ease nausea in chemotherapy patients. Based on the research of Anwar Hussain and Lewis Dittert, pharmacy.
Niadyne Inc.
(October 2000)
2509 North Campbell Avenue (#138) Tucson, AZ 85719-3362
520/250-7532
www.niadyne.com
Develops topical products designed to enhance skin health and appearance through the prevention and repair of cellular damage. Based on the research of Elaine Jacobson, formerly in allied health professions, and Mike Jacobson, formerly in pharmacy.
Phoenix Pharmacologics Inc.
(July 2002)
1517 Nicholasville Road (Suite 402)
Lexington, KY 40503-1429
859/277-8890
www.phoenixpharm.org
Develops novel biological anti-cancer drug; four drugs that treat eight types of cancer are in clinical development. Based on the research of Mike Clark and inventions from the Ludwig Institute for Cancer Research in San Diego, CA.
Prescient Medical Inc.
(June 2005)
Quanteon L.L.C.
(November 2005)
SenTech Corporation
(July 2001)
430 Bailey Lane, Boalsburg, PA 16827-1315
814/466-8751
Develops miniature sensors to measure temperature, pressure, viscosity, surface tension, humidity and glucose concentrations. Based on the research of Craig Grimes, formerly in electrical engineering.
Spectral Research Inc.
(March 2002)
1748 Brook Park Drive
Lexington, KY 40515-1309
859/272-5082
Develops optical imaging equipment for use in minimally invasive surgery, including a 3-D imaging system to achieve real time improvements in surgical vision. Based on the work of Michael F. Shaw, Center for Minimally Invasive Surgery.
TIgen Pharmaceuticals Inc.
(November 1999)
235 Bolivar Street, Lexington, KY 40508-2931
859/388-9444
www.tigen.com
Focuses on Topoisomerase Inhibition (TI), for the selective delivery of drugs to target tissues. Founded in 1998 and based on the research of the late Thomas Burke, pharmacy.
Venture Laboratories Inc.
(May 2003)